Acetyl-CoA acyltransferase 1 (ACAA1) features as a key regulator of fatty acid β-oxidation in peroxisomes by catalyzing the cleavage of 3-ketoacyl-CoA to acetyl-CoA and acyl-CoA, which take part in the extension and degradation of fatty acids. Thus, ACAA1 is a vital regulator of lipid metabolism and performs a necessary function in fatty acid oxidation and lipid metabolism. Our earlier examine findings revealed that ACAA1 is intently related to the peroxisome proliferator-activated receptor (PPAR) signaling and fatty acid metabolism pathways, that are concerned in fats deposition in sheep, resulting in our speculation that ACAA1 could also be concerned in fats deposition by regulating lipid metabolism.
However, the related molecular mechanism stays unclear. In the current examine, to evaluate the potential operate of ACAA1 in sheep preadipocyte differentiation, we knocked down and overexpressed ACAA1 in sheep preadipocytes and evaluated the sample of ACAA1 gene expression throughout preadipocyte differentiation by qRT-PCR. ACAA1 was considerably expressed in the early stage of adipocyte differentiation, after which its expression decreased.
ACAA1 deficiency elevated lipid accumulation and the triglyceride content material and promoted sheep preadipocyte differentiation, whereas ACAA1 overexpression inhibited adipogenesis and decreased lipid accumulation and the triglyceride content material. Simultaneously, we demonstrated that ACAA1 deficiency upregulated the expressions of the adipogenic marker genes PPARγ and C/EBPα in sheep preadipocytes, however ACAA1 overexpression inhibited the expressions of these markers, indicating that ACAA1 impacts lipid metabolism by regulating adipogenic marker genes. Our outcomes might promote a greater understanding of the regulation of adipogenesis by ACAA1.
The molecular foundation for SARS-CoV-2 binding to canine ACE2
SARS-CoV-2 can infect many home animals, together with canines. Herein, we present that canine angiotensin-converting enzyme 2 (dACE2) can bind to the SARS-CoV-2 spike (S) protein receptor binding area (RBD), and that each pseudotyped and genuine SARS-CoV-2 can infect dACE2-expressing cells. We solved the crystal construction of RBD in advanced with dACE2 and located that the whole quantity of contact residues, contact atoms, hydrogen bonds and salt bridges at the binding interface in this advanced are barely fewer than these in the advanced of the RBD and human ACE2 (hACE2).
This result’s in line with the proven fact that the binding affinity of RBD to dACE2 is decrease than that of hACE2. We additional present that a number of vital mutations in the RBD binding interface play a pivotal function in the binding affinity of RBD to each dACE2 and hACE2. Our work reveals a molecular foundation for cross-species transmission and potential animal unfold of SARS-CoV-2, and offers new clues to dam the potential transmission chains of this virus.
Ependymal cells-CSF circulate regulates stress-induced melancholy
Major depressive dysfunction (MDD) is a extreme, widespread temper dysfunction. While decreased cerebrospinal fluid (CSF) circulate adversely impacts mind metabolism and fluid stability in the growing older inhabitants and through improvement, solely oblique proof hyperlinks aberrant CSF circulation with many ailments together with neurological, neurodegenerative, and psychiatric issues, resembling nervousness and melancholy. Here we present a really excessive focus of p11 as a key molecular determinant for melancholy in ependymal cells, which is considerably decreased in sufferers with MDD, and in two mouse fashions of melancholy induced by continual stress, resembling restraint and social isolation.
The loss of p11 in ependymal cells causes disoriented ependymal planar cell polarity (PCP), decreased CSF circulate, and depression-like and anxiety-like behaviors. p11 intrinsically controls PCP core genes, which mediates CSF circulate. Viral expression of p11 in ependymal cells particularly rescues the pathophysiological and behavioral deficits brought on by loss of p11. Taken collectively, our outcomes determine a brand new function and a key molecular determinant for ependymal cell-driven CSF circulate in temper issues and recommend a novel technique for improvement of therapies for stress-associated neurological, neurodegenerative, and psychiatric issues.
Differential binding of SARS-CoV-2 Spike protein variants to its cognate receptor hACE2 utilizing molecular modeling based mostly binding evaluation
The present emergence of novel coronavirus, SARS-CoV-2 and its ceaseless enlargement worldwide has posed a worldwide well being emergency that has adversely affected the people. With the total world striving to grasp the newly emerged virus, variations in morbidity and an infection fee of SARS-CoV-2 have been noticed throughout diverse geographic areas, which have been ascribed to viral mutation and evolution over time. The homotrimeric Spike (S) glycoprotein on the viral envelope floor is accountable for binding, priming, and initiating an infection in the host.
Our phylogeny evaluation of 1947 sequences of S proteins indicated there’s a change in amino acid (aa) from aspartate (Group-A) to glycine (Group-B) at place 614, close to the receptor- binding area (RBD; aa positions 331-524). The two variants are reported to be in circulation, disproportionately throughout the world, with Group-A dominant in Asia and Group-B in North America.
The trimeric, monomeric, and RBD of S protein of each the variant teams (A & B) have been modeled utilizing the Swiss-Model server and have been docked with the human receptor angiotensin-converting enzyme 2 (hACE2) using the PatchDock server and visualized in PyMol. Group-A S protein’s RBD certain imperceptibly to the two binding clefts of the hACE2 protein, on the different hand, Group-B S protein’s RBD completely interacted inside the binding clefts of hACE2, with larger quantity of hydrogen and hydrophobic interactions.
Phenol, crystalline |
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| PB4112 | Bio Basic | 500g | EUR 210.34 |
Acrylamide 3x cryst. for molecular biology, 99.9% |
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| 61346 | Sisco Laboratories | 100 Gms | EUR 5.47 |
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Description: Part A |
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Phenol Equilibrated with 0.1M Citrate Buffer pH 4.5 for molecular biology w/ Stabilizer |
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| 47484 | Sisco Laboratories | 100 ml | EUR 7.39 |
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Description: Part A |
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Phenol:Chloroform:Isoamyl Alcohol (125:24:1) pH 4.5 for molecular biology |
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| 17080 | Sisco Laboratories | 100 ml | EUR 19.29 |
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Description: Part A |
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Phenol:Chloroform:Isoamyl Alcohol (25:24:1) pH 8.0 for molecular biology |
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| 69031 | Sisco Laboratories | 100 ml | EUR 10.4 |
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Description: Part A |
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Phenol:Chloroform:Isoamyl Alcohol (49.5:49.5:1) pH 6.7 for molecular biology |
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| 79030 | Sisco Laboratories | 100 ml | EUR 20.18 |
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Description: Part A |
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Phenol Crystalline pure, 99% |
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| 28104 | Sisco Laboratories | 500 Gms | EUR 3.97 |
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Description: Part A |
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Phenol:Chloroform: Isoamyl Alcohol (49.5:49.5:1) pH 8.0 for molecular biology |
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| 36976 | Sisco Laboratories | 100 ml | EUR 21.07 |
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Description: Part A |
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Phenol Crystalline extrapure AR, 99.5% |
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| 14892 | Sisco Laboratories | 500 Gms | EUR 4.45 |
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Description: Part A |
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Lysozyme (3x cryst) ex. Egg white (Muramidase) for molecular biology, 15000U/mg |
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| 45822 | Sisco Laboratories | 1 Gms | EUR 6.3 |
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Description: Part B |
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Casein, for Molecular Biology |
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| MB279-100G | EWC Diagnostics | 1 unit | EUR 110.77 |
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Description: Casein, for Molecular Biology |
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Casein, for Molecular Biology |
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| MB279-500G | EWC Diagnostics | 1 unit | EUR 387.65 |
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Description: Casein, for Molecular Biology |
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N,N-Methylene Bisacrylamide 3x cryst. for molecular biology, 99.5% |
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| 67320 | Sisco Laboratories | 25 Gms | EUR 3.97 |
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Description: Part A |
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Sucrose for molecular biology |
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| 27580 | Sisco Laboratories | 500 Gms | EUR 4.11 |
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Description: Part A |
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Urea for molecular biology, 99.5% |
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| 21113 | Sisco Laboratories | 500 Gms | EUR 6.5 |
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Description: Part A |
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Xylene for molecular biology, 99.5% |
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| 45122 | Sisco Laboratories | 250 ml | EUR 2.81 |
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Description: Part A |
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Glycine for molecular biology, 99.5% |
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| 64072 | Sisco Laboratories | 100 Gms | EUR 1.64 |
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Description: Part A |
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Acetone for molecular biology, 99.8% |
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| 27498 | Sisco Laboratories | 500 ml | EUR 3.76 |
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Description: Part A |
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Methanol for molecular biology, 99.5% |
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| 96446 | Sisco Laboratories | 500 ml | EUR 6.23 |
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Description: Part A |
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Carbinol for molecular biology, 99.5% |
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| 34883 | Sisco Laboratories | 500 ml | EUR 6.23 |
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Description: Part A |
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Formamide for molecular biology, 99.5% |
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| 30349 | Sisco Laboratories | 500 ml | EUR 5.82 |
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Description: Part A |
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Imidazole for molecular biology, 99.5% |
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| 61510 | Sisco Laboratories | 25 Gms | EUR 5.47 |
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Description: Part A |
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Chloroform for molecular biology, 99.8% |
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| 96764 | Sisco Laboratories | 100 ml | EUR 3.08 |
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Description: Part A |
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Urea, suitable for molecular biology |
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| GE1210 | Glentham Life Sciences | 500g | EUR 53.1 |
Urea, suitable for molecular biology |
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| GE1210-1 | Glentham Life Sciences | 1 | EUR 58 |
Urea, suitable for molecular biology |
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| GE1210-1KG | Glentham Life Sciences | 1 kg | EUR 106.8 |
Urea, suitable for molecular biology |
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| GE1210-500 | Glentham Life Sciences | 500 | EUR 33.1 |
Urea, suitable for molecular biology |
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| GE1210-500G | Glentham Life Sciences | 500 g | EUR 76.8 |
Triethylamine for molecular biology, 99.5% |
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| 55221 | Sisco Laboratories | 500 ml | EUR 4.11 |
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Description: Part A |
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Ficoll 400® for molecular biology |
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| 45460 | Sisco Laboratories | 5 Gms | EUR 15.6 |
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Description: Part B |
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Agarose UltraPhor for molecular biology |
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| 27813 | Sisco Laboratories | 10 Gms | EUR 46.5 |
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Description: Part B |
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Boric Acid for molecular biology, 99.5% |
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| 22311 | Sisco Laboratories | 250 Gms | EUR 4.04 |
|
Description: Part A |
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2-Mercaptoethanol ?For Molecular Biology |
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| MB041-100ML | EWC Diagnostics | 1 unit | EUR 9.02 |
|
Description: 2-Mercaptoethanol ?For Molecular Biology |
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2-Mercaptoethanol ?For Molecular Biology |
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| MB041-500ML | EWC Diagnostics | 1 unit | EUR 26.47 |
|
Description: 2-Mercaptoethanol ?For Molecular Biology |
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Vitamin B12 for molecular biology, 97% |
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| 77472 | Sisco Laboratories | 250 Mg | EUR 5.78 |
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Description: Part B |
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Triton X-100 for molecular biology |
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| 64518 | Sisco Laboratories | 100 ml | EUR 6.02 |
|
Description: Part A |
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MOPS Buffer for molecular biology, 99% |
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| 66043 | Sisco Laboratories | 25 Gms | EUR 10.28 |
|
Description: Part B |
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ACES Buffer for molecular biology, 99.5% |
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| 27907 | Sisco Laboratories | 5 Gms | EUR 5.4 |
|
Description: Part B |
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Agarose Low EEO for molecular biology |
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| 36601 | Sisco Laboratories | 10 Gms | EUR 5.1 |
|
Description: Part B |
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PIPES Buffer for molecular biology, 99% |
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| 49159 | Sisco Laboratories | 100 Gms | EUR 26.03 |
|
Description: Part B |
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10X MOPS Buffer for molecular biology |
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| 68078 | Sisco Laboratories | 100 ml | EUR 4.5 |
|
Description: Part B |
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CHAPS Buffer for molecular biology, 99.5% |
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| 21420 | Sisco Laboratories | 1 Gms | EUR 10.73 |
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Description: Part B |
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HEPES Buffer for molecular biology, 99.5% |
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| 16826 | Sisco Laboratories | 25 Gms | EUR 6.3 |
|
Description: Part B |
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Sodium Azide for molecular biology, 99% |
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| 17782 | Sisco Laboratories | 100 Gms | EUR 5.47 |
|
Description: Part A |
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Phenylmethane Sulphonyl Fluoride (PMSF) for molecular biology, 99% |
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| 84375 | Sisco Laboratories | 1 Gms | EUR 7.13 |
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Description: Part B |
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Agarose High EEO for molecular biology |
|||
| 60645 | Sisco Laboratories | 25 Gms | EUR 13.8 |
|
Description: Part B |
|||
Jasmonic Acid for molecular biology, 95% |
|||
| 79238 | Sisco Laboratories | 25 Mg | EUR 120.9 |
|
Description: Part B |
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Protamine Sulfate for molecular biology, 90-110% |
|||
| 78349 | Sisco Laboratories | 1 Gms | EUR 22.5 |
|
Description: Part B |
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Oil Red O for molecular biology, 75% |
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| 23576 | Sisco Laboratories | 25 Gms | EUR 5.33 |
|
Description: Part B |
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Agarose Medium EEO for molecular biology |
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| 10423 | Sisco Laboratories | 10 Gms | EUR 6.75 |
|
Description: Part B |
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Isopropanol (IPA) for molecular biology, 99.8% |
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| 38445 | Sisco Laboratories | 100 ml | EUR 1.71 |
|
Description: Part A |
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Sodium Chloride for molecular biology, 99.9% |
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| 33205 | Sisco Laboratories | 500 Gms | EUR 4.52 |
|
Description: Part A |
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Ethidium Bromide for molecular biology, 95% |
|||
| 93079 | Sisco Laboratories | 1 Gms | EUR 4.58 |
|
Description: Part A |
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Ammonium Acetate for molecular biology, 98% |
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| 37829 | Sisco Laboratories | 100 Gms | EUR 2.12 |
|
Description: Part A |
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Agarose Low Melting for molecular biology |
|||
| 32417 | Sisco Laboratories | 5 Gms | EUR 22.5 |
|
Description: Part B |
|||
Acetonitrile (ACN) for molecular biology, 99.9% |
|||
| 62006 | Sisco Laboratories | 250 ml | EUR 4.93 |
|
Description: Part A |
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Potassium Acetate for molecular biology, 99.5% |
|||
| 96248 | Sisco Laboratories | 100 Gms | EUR 2.74 |
|
Description: Part A |
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Ammonium Sulphate for molecular biology, 99.5% |
|||
| 82126 | Sisco Laboratories | 250 Gms | EUR 4.93 |
|
Description: Part A |
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Ammonium Chloride for molecular biology, 99.5% |
|||
| 16992 | Sisco Laboratories | 500 Gms | EUR 4.52 |
|
Description: Part A |
|||
Potassium Chloride for molecular biology, 99.5% |
|||
| 84984 | Sisco Laboratories | 500 Gms | EUR 6.16 |
|
Description: Part A |
|||
Sodium Bicarbonate for molecular biology, 99.7% |
|||
| 36328 | Sisco Laboratories | 500 Gms | EUR 5.47 |
|
Description: Part A |
|||
Glycerol (Glycerine) for molecular biology, 99.5% |
|||
| 62417 | Sisco Laboratories | 100 ml | EUR 2.05 |
|
Description: Part A |
|||
2-Mercaptoethanol for molecular biology, 99% |
|||
| 83759 | Sisco Laboratories | 100 ml | EUR 5.27 |
|
Description: Part A |
|||
Tetrahydrofuran (THF) for molecular biology, 99.8% |
|||
| 92562 | Sisco Laboratories | 250 ml | EUR 3.28 |
|
Description: Part A |
|||
Acriflavine Neutral for molecular biology, 98% |
|||
| 42428 | Sisco Laboratories | 5 Gms | EUR 3.15 |
|
Description: Part B |
|||
Dichloromethane (DCM) for molecular biology, 99.9% |
|||
| 41512 | Sisco Laboratories | 250 ml | EUR 3.22 |
|
Description: Part A |
|||
Dithioerythritol (DTE) for molecular biology, 99% |
|||
| 53384 | Sisco Laboratories | 1 Gms | EUR 9.53 |
|
Description: Part B |
|||
Sodium chloride, suitable for molecular biology |
|||
| GE0307 | Glentham Life Sciences | 1kg | EUR 41.33 |
Sodium chloride, suitable for molecular biology |
|||
| GE0307-1 | Glentham Life Sciences | 1 | EUR 45.2 |
HEPES Sodium Salt for molecular biology, 99% |
|||
| 32225 | Sisco Laboratories | 25 Gms | EUR 11.85 |
|
Description: Part B |
|||
meta-Topolin (mT) for molecular biology, 98% |
|||
| 68913 | Sisco Laboratories | 25 Mg | EUR 17.48 |
|
Description: Part B |
|||
L-Ascorbic Acid for molecular biology, 99.7% |
|||
| 14116 | Sisco Laboratories | 25 Gms | EUR 1.64 |
|
Description: Part A |
|||
Sucrose, GlenBiol, suitable for molecular biology |
|||
| GC3201-1KG | Glentham Life Sciences | 1 kg | EUR 90 |
Glycogen ex. Oyster for molecular biology, 85% |
|||
| 49740 | Sisco Laboratories | 1 Gms | EUR 7.5 |
|
Description: Part B |
|||
Acetic Acid Glacial for molecular biology, 99.9% |
|||
| 59788 | Sisco Laboratories | 100 ml | EUR 3.56 |
|
Description: Part A |
|||
D-Sorbitol Powder for molecular biology, 98% |
|||
| 99103 | Sisco Laboratories | 500 Gms | EUR 10.33 |
|
Description: Part A |
|||
Brilliant Blue R-250 for molecular biology |
|||
| 93473 | Sisco Laboratories | 5 Gms | EUR 4.35 |
|
Description: Part B |
|||
Brilliant Blue G-250 for molecular biology |
|||
| 64222 | Sisco Laboratories | 5 Gms | EUR 4.65 |
|
Description: Part B |
|||
Propidium Iodide (PI) for molecular biology, 95% |
|||
| 11195 | Sisco Laboratories | 10 Mg | EUR 17.63 |
|
Description: Part B |
|||
Acriflavine Hydrochloride for molecular biology, 98.5%-105% |
|||
| 35188 | Sisco Laboratories | 5 Gms | EUR 4.05 |
|
Description: Part B |
|||
Tris Buffer Superior for molecular biology, 99.9% |
|||
| 37969 | Sisco Laboratories | 100 Gms | EUR 7.59 |
|
Description: Part A |
|||
Polysorbate 20 (Tween 20) for molecular biology |
|||
| 65296 | Sisco Laboratories | 100 Gms | EUR 10.81 |
|
Description: Part A |
|||
Molecular Biology Grade Water for RT-PCR |
|||
| ML065-1.5ML | EWC Diagnostics | 1 unit | EUR 7.82 |
|
Description: Molecular Biology Grade Water for RT-PCR |
|||
10X TE Buffer pH-8.0 for molecular biology |
|||
| 51782 | Sisco Laboratories | 100 ml | EUR 9.45 |
|
Description: Part B |
|||
10X TBE Buffer pH-8.3 for molecular biology |
|||
| 83170 | Sisco Laboratories | 200 ml | EUR 4.95 |
|
Description: Part B |
|||
Tris Buffer AR, ACS for molecular biology, 99.9% |
|||
| 71033 | Sisco Laboratories | 100 Gms | EUR 6.02 |
|
Description: Part A |
|||
10X TAE Buffer pH-8.3 for molecular biology |
|||
| 71989 | Sisco Laboratories | 100 ml | EUR 4.43 |
|
Description: Part B |
|||
Acrylamide 40% aq. solution for molecular biology |
|||
| 29787 | Sisco Laboratories | 250 ml | EUR 20.53 |
|
Description: Part A |
|||
MES Monohydrate Buffer for molecular biology, 99% |
|||
| 26854 | Sisco Laboratories | 25 Gms | EUR 11.03 |
|
Description: Part B |
|||
DL-Dithiothreitol (DTT) for molecular biology, 98% |
|||
| 17315 | Sisco Laboratories | 1 Gms | EUR 5.18 |
|
Description: Part B |
|||
Glutathione Reduced (GSH) for molecular biology, 99.5% |
|||
| 11514 | Sisco Laboratories | 1 Gms | EUR 5.55 |
|
Description: Part B |
|||
Ammonium Persulphate (APS) for molecular biology, 99% |
|||
| 65553 | Sisco Laboratories | 25 Gms | EUR 1.64 |
|
Description: Part A |
|||
Trifluoroacetic Acid (TFA) for molecular biology, 99.9% |
|||
| 40801 | Sisco Laboratories | 100 ml | EUR 22.92 |
|
Description: Part A |
|||
Sodium Acetate Anhydrous for molecular biology, 99% |
|||
| 22342 | Sisco Laboratories | 250 Gms | EUR 3.56 |
|
Description: Part A |
|||
Dimethyl Sulphoxide (DMSO) for molecular biology, 99.8% |
|||
| 24075 | Sisco Laboratories | 100 ml | EUR 6.02 |
|
Description: Part A |
|||
Cesium Sulphate extrapure for molecular biology, 99.9% |
|||
| 57455 | Sisco Laboratories | 10 Gms | EUR 7.5 |
|
Description: Part B |
|||
Sodium Acetate Trihydrate for molecular biology, 99.5% |
|||
| 88035 | Sisco Laboratories | 250 Gms | EUR 2.33 |
|
Description: Part A |
|||
Cesium Chloride ultrapure for molecular biology, 99.9% |
|||
| 32355 | Sisco Laboratories | 25 Gms | EUR 18 |
|
Description: Part B |
|||
Guanidine Thiocyanate (GTC) for molecular biology, 99% |
|||
| 80272 | Sisco Laboratories | 100 Gms | EUR 5.47 |
|
Description: Part A |
|||
Glutathione Oxidized (GSSG) for molecular biology, 99.5% |
|||
| 22151 | Sisco Laboratories | 250 Mg | EUR 22.5 |
|
Description: Part B |
|||
Sucrose, GlenBiol™, suitable for molecular biology |
|||
| GC3201 | Glentham Life Sciences | 1kg | EUR 41.25 |
Sucrose, GlenBiol™, suitable for molecular biology |
|||
| GC3201-1 | Glentham Life Sciences | 1 | EUR 45.1 |
Pyridine, GlenBiol™, suitable for molecular biology with molecular sieve |
|||
| GS8780 | Glentham Life Sciences | 2500ml | EUR 239.63 |
Pyridine, GlenBiol™, suitable for molecular biology with molecular sieve |
|||
| GS8780-2500 | Glentham Life Sciences | 2500 | EUR 249.8 |
Calcium Chloride Dihydrate for molecular biology, 99.5% |
|||
| 97080 | Sisco Laboratories | 100 Gms | EUR 2.12 |
|
Description: Part A |
|||
Diethyl Pyrocarbonate (DEPC) for molecular biology, 99% |
|||
| 46791 | Sisco Laboratories | 5 ml | EUR 9 |
|
Description: Part B |
|||
Pyridine, GlenBiol™, suitable for molecular biology |
|||
| GS6659 | Glentham Life Sciences | 500ml | EUR 230.38 |
Pyridine, GlenBiol™, suitable for molecular biology |
|||
| GS6659-2500 | Glentham Life Sciences | 2500 | EUR 240.3 |
Pyridine, GlenBiol™, suitable for molecular biology |
|||
| GS6659-500 | Glentham Life Sciences | 500 | EUR 95.8 |
Formamide, GlenBiol™, suitable for molecular biology |
|||
| GS9663 | Glentham Life Sciences | 100ml | EUR 46.83 |
Formamide, GlenBiol™, suitable for molecular biology |
|||
| GS9663-100 | Glentham Life Sciences | 100 | EUR 48.9 |
20X SSC Buffer pH 6.9-7.1 for molecular biology |
|||
| 12590 | Sisco Laboratories | 200 ml | EUR 2.48 |
|
Description: Part B |
|||
Guanidine Hydrochloride (GHC) for molecular biology, 99.5% |
|||
| 45539 | Sisco Laboratories | 100 Gms | EUR 4.79 |
|
Description: Part A |
|||
Bromocresol Purple Sodium Salt for molecular biology |
|||
| 24836 | Sisco Laboratories | 5 Gms | EUR 2.05 |
|
Description: Part A |
|||
Phenol Crystalline extrapure AR, ACS, ExiPlus, Multi-Compendial, 99.5% |
|||
| 97745 | Sisco Laboratories | 500 Gms | EUR 4.93 |
|
Description: Part A |
|||
Polyethylene Glycol 8000 (PEG 8000) for molecular biology |
|||
| 54866 | Sisco Laboratories | 500 Gms | EUR 11.97 |
|
Description: Part A |
|||
10X Tris Buffered Saline (TBS) for molecular biology |
|||
| 83471 | Sisco Laboratories | 500 ml | EUR 14.7 |
|
Description: Part B |
|||
Magnesium Acetate Tetrahydrate for molecular biology, 99% |
|||
| 50488 | Sisco Laboratories | 100 Gms | EUR 2.74 |
|
Description: Part A |
|||
Magnesium Chloride Hexahydrate for molecular biology, 99.5% |
|||
| 91417 | Sisco Laboratories | 250 Gms | EUR 4.45 |
|
Description: Part A |
|||
Magnesium Sulphate Heptahydrate for molecular biology, 99.5% |
|||
| 74440 | Sisco Laboratories | 500 Gms | EUR 6.16 |
|
Description: Part A |
|||
Tris Hydrochloride (Tris HCl) for molecular biology, 99% |
|||
| 89781 | Sisco Laboratories | 100 Gms | EUR 9.37 |
|
Description: Part A |
|||
Agarose Low EEO Superior Grade for molecular biology |
|||
| 23287 | Sisco Laboratories | 10 Gms | EUR 6 |
|
Description: Part B |
|||
L-Lysine Monohydrate (base) for molecular biology, 99% |
|||
| 45976 | Sisco Laboratories | 25 Gms | EUR 37.63 |
|
Description: Part A |
|||
OORA00229-1L - Molecular Biology Grade UltraPure Water |
|||
| OORA00229-1L | Aviva Systems Biology | 1L | EUR 149 |
OORA00230-1L - Molecular Biology Grade UltraPure Water |
|||
| OORA00230-1L | Aviva Systems Biology | 1L | EUR 279 |
DTT (Molecular Biology Grade) |
|||
| CE131 | GeneOn | 5 g | EUR 44 |
DTT (Molecular Biology Grade) |
|||
| CE132 | GeneOn | 10 g | EUR 88 |
DTT (Molecular Biology Grade) |
|||
| CE133 | GeneOn | 25 g | EUR 170 |
NAD (Molecular Biology Grade) |
|||
| CE196 | GeneOn | 1 g | EUR 34 |
NAD (Molecular Biology Grade) |
|||
| CE197 | GeneOn | 5 g | EUR 137 |
NBT (Molecular Biology Grade) |
|||
| CE209 | GeneOn | 1 g | EUR 96 |
NBT (Molecular Biology Grade) |
|||
| CE210 | GeneOn | 5 g | EUR 345 |
10X Tris-Glycine-SDS Buffer for molecular biology |
|||
| 57806 | Sisco Laboratories | 200 ml | EUR 3.6 |
|
Description: Part B |
|||
10X Tris-Tricine-SDS Buffer for molecular biology |
|||
| 37852 | Sisco Laboratories | 500 ml | EUR 9.08 |
|
Description: Part B |
|||
Cesium Chloride extrapure AR for molecular biology, 99.9% |
|||
| 22966 | Sisco Laboratories | 25 Gms | EUR 14.63 |
|
Description: Part B |
|||
N,N-Dimethylformamide (DMF) for molecular biology, 99.9% |
|||
| 24017 | Sisco Laboratories | 100 ml | EUR 3.08 |
|
Description: Part A |
|||
EDTA Disodium Salt Dihydrate for molecular biology, 99.5% |
|||
| 43272 | Sisco Laboratories | 100 Gms | EUR 2.26 |
|
Description: Part A |
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DMSO, Molecular Biology Grade |
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| 40470006-1 | Bio-WORLD | 100 mL | EUR 108.14 |
DMSO, Molecular Biology Grade |
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| 40470006-2 | Bio-WORLD | 250 mL | EUR 182.67 |
DMSO, Molecular Biology Grade |
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| 40470006-3 | Bio-WORLD | 500 mL | EUR 342.49 |
EGTA, Molecular Biology Grade |
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| 40500028-2 | Bio-WORLD | 50 g | EUR 130.53 |
EGTA, Molecular Biology Grade |
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| 40500028-3 | Bio-WORLD | 100 g | EUR 217.78 |
EGTA, Molecular Biology Grade |
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| 40500028-4 | Bio-WORLD | 500 g | EUR 734.55 |
EGTA, Molecular Biology Grade |
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| 40500028-5 | Bio-WORLD | 1 kg | EUR 1119.67 |
This implies that the S protein’s amino acid at place 614 close to the core RBD influences its interplay with the cognate hACE2 receptor, which can induce its infectivity that ought to be explored additional with molecular and biochemical research.
